03479nam a22004334a 4500001001000000003000700010005001700017006001900034007001500053008004100068016000900109020003600118020002700154035002200181035002300203035002500226035002300251035002100274040004100295050002300336082001500359245012300374260004800497300002600545504005100571505091100622505101501533590014702548650004702695650002702742650002902769650003002798655002902828700002502857710002802882797002002910856009602930999001903026EBC427896MiAaPQ20250821104339.0m     o  d |      cr cnu||||||||080303s2009    njua    ob    001 0 eng  7 2DNLM  a9780470386354q(electronic bk.)  z9780470056097q(print)  a(MiAaPQ)EBC427896  a(Au-PeEL)EBL427896  a(CaPaEBR)ebr10296483  a(CaONFJC)MIL203105  a(OCoLC)437111461  aMiAaPQbengerdaepncMiAaPQdMiAaPQ 4aRM301.8b.F67 20090 a615/.122200aFormulation and analytical development for low-dose oral drug productsh[electronic resource] /cedited by Jack Zheng.  aHoboken, N.J. :bJohn Wiley & Sons,cc2009.  axxiii, 461 p. :bill.  aIncludes bibliographical references and index.0 aAn overview / Jack Y. Zheng -- Challenges and strategies in formulation development of oral solid low-dose drug products / Jack Y. Zheng -- Particle size of drug substance and product content uniformity: theoretical considerations / Kevin C. Johnson -- Development of low-dose formulations using fluidized bed granulation / J. Joe Zhou, and Ralph Lipp -- Development of low-dose solid oral formulations using wet granulation / Ahmad Almaya -- Challenges in development and scale-up of low dose drug products by dry granulation: a case study / Mary T. Am Ende ... [et al.] -- Development of low-dose solid oral tablets using direct compression / Jack Y. Zheng and Robert L. Ternik -- Reduction of particle size of drug substance for low-dose drug products / Christopher L. Burcham ... [et al.] -- Function, quality, and regulations of pharmaceutical excipients for oral solid dosage forms / Jack Y. Zheng --0 aAnalytical method development: challenges and solutions for low-dose oral dosage forms / Beverly Nickerson ... [et al.] -- In vitro dissolution testing and method development / Vivian A. Gray, Jack Y. Zheng, and Norman N. Sesi -- Analysis of physical transformation of API during manufacture and storage / Gregory A. Stephenson -- Physical characterization tests for drug substances used in low-dose formulations / Ronald G. Lacocca -- An excipient library approach to analytical development for low-dose, solid oral dosage form drug products / Qing Chang ... [et al.] -- Cleaning verification for highly potent compounds / Brian W. Pack -- Containment challenges and strategies for potent compounds in the pharmaceutical industry / Victoria Cathcart, Sarah Jones, Beverly Nickerson -- Sample handling and containment in analytical testing laboratories / David Pattavina, Nancy Sage, Beverly Nickerson -- Regulatory considerations in the development of low-dose solid oral drug products / Ravi S. Harapanhalli.  aElectronic reproduction. Ann Arbor, MI : ProQuest, 2018. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. 0aDrugsxDose-response relationship.9192672 0aDrugsxDosage.9192673 0aOral medication.9192674 0aDrug development.9192675 4aElectronic books.9351421 aZheng, Jack.91926762 aProQuest (Firm)91926772 aProQuest (Firm)40uhttps://ebookcentral.proquest.com/lib/kuct-ebooks/detail.action?docID=427896zClick to View  c247871d247871